Satan Challenges


Welcome to The Binding of Isaac challenge guide. Click on a challenge to learn more.

Order
Featured
Hearts (with Amounts)
Conditions
Goal
Unlocks

Ultra Hard

34
3 Red Hearts
Key Piece 1, Key Piece 2, Curse of the Labyrinth, Curse of the Blind, Curse of the Lost, Curse of the Maze
Samson Feels Healthy!
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I RULE!

26
3 Red Hearts
The Boomerang, Key Piece 1, Key Piece 2, The Ladder, Mom's Knife, Trinity Shield
Poker Chip
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Blue Bomber

23
3 Soul Hearts, Blindfolded
Brother Bobby, Kamikaze!, Pyromaniac, Mr. Mega
Gold Bomb
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Darkness Falls

4
2 Red Hearts
Pentagram, Dead Bird, Whore of Babylon, Razor Blade, Sacrificial Dagger, Dark Matter
Rune of Dagaz
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