Spawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
Chaos causes items to be chosen from random item pools. When picked up, drops between 1-6 random pickups on the floor.
Money = Power
Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins.
After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.
Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.
Two items spawn in every Treasure Room. Only one can be taken; the other will disappear.
Adds a chance to shoot a fire that damages enemies and remains in place until it deals enough damage or the room is left.
Eye of Greed
Adds a chance to fire tears that temporarily stun enemies and turn them into gold. Any enemy killed while in this state will drop coins.
Taking damage releases a ring of 10 high damage tears.
Increases damage and speed, removes all red heart containers, grants six black hearts, and adds a chance to shoot fear tears.
Gives Isaac's tears a boomerang effect, and increases range and shot speed.
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
Adds a chance to fire a gas cloud that damages nearby enemies.
A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.
Sets your key count to the maximum of 99.
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.