4 rooms Items
The Book of Sin
Spawns a random pickup, pill, card, or trinket.
Crack the Sky
Summons multiple beams of light in random locations around the room, dealing a large amount of damage to any enemy that touches them.
Has the same effect as the card or rune currently held by Isaac.
Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies.
Upon use, spawns a sprinkler that rotates and fires tears.
Summons a controllable ghost that can perform various tasks depending on what it targets.
If the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room.
Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in The Dark Room.
Displaces enemy sprites for the current room and increases or decreases a random stat.
Spawns a penny and has a 50% chance to double all items and pickups in the room. If the effect fails, the items and pickups disappear.
While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.
Book of the Dead
Upon use, spawns a charmed Bony or an orbital bone for each enemy killed in the current room.
Throws a black hole on the ground which sucks in and damages enemies.
When used, teleports Isaac to a random room that has not been explored yet. If all rooms are explored, including secret rooms, it will teleport Isaac to the Devil or Angel room. If all rooms are explored, including the Devil or Angel room, it will teleport Isaac to the I AM ERROR room. If used in a room with enemies, it will teleport Isaac out and back into the exact same room.
When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.
When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.