Item: A Pony
Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal.
When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.
Duplicates all pickups and item pedestals in the room.
Forget Me Now
When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
When used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
Re-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poops.
When used, converts two soul hearts into a heart container.
Removes a heart container, increases damage and range, and grants a Cube of Meat.
Rerolls the enemies in a room. Only rerolls enemies that are still alive (does not spawn new enemies).
Upon use, turns Isaac's head into a stationary familiar for the current room which fires normal tears that deal 3.5 damage.
When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.
When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head.
Throws a black hole on the ground which sucks in and damages enemies.
For 1 coin, damages all enemies in the room.
Freezes all enemies until a fire button is pressed.
Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears.
Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack the Sky.
Upon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the blood donation machine.