Item: A Quarter
+1 luck. Spawns a fairy familiar that points out secret room entrances and tinted rocks.
Adds a chance to fire a booger which sticks to enemies and poisons them.
Isaac's tears split in two when they hit something.
Increases damage and increases the chance for a Devil or Angel Room to appear.
Isaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage.
A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Head of the Keeper
Isaac's tears become coins and now have a chance to drop pennies on the floor upon successfully hitting an enemy.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).
Grants one soul heart. Upon entering a boss room, grants a shield that blocks one hit, then disappears.
Spawns a white poop familiar, which turns into a white poop when Isaac is hurt.
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
Increases Shot Speed and damage.
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.
+0.7 tears up. Grants a random item at the start of the next run.
+1.7 tears, +0.3 speed, reduces damage.