Grants a random Harbinger familiar that changes every 10 seconds.
Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
Spawns allied blue spiders from killed enemies.
Adds 3 soul hearts. Grants The Wafer effect for the current room upon taking damage.
Dad's Lost Coin
Increases range by 1.5. Drops a lucky penny.
Tears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed.
Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
A familiar that follows Isaac and blocks tears. If a tear hits Farting Baby, there is a high chance for it to fart, which will either knock back, poison, or charm all nearby enemies.
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
A familiar that mirrors the player's movements and shoots in the opposite direction.
Makes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased . If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.
Drops a random card or rune. Doubles the effects of cards and runes.
Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.
Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.
Reveals all rooms for every floor. However, it does not reveal icons or secret rooms.
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).
An orbital angel which does 7 contact damage per tick and blocks enemy shots. Upon blocking 10 shots in a room it drops an eternal heart.