Item: Book of the Dead

Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be charmed until it dies, persisting between floors.

Creates a trapdoor to go to the next floor. If used in The Womb, it will create a trapdoor to Sheol, even if the player hasn't unlocked it.

Re-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poops.

Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.

Creates a small yellow pool of creep, which damages enemies that cross it.

Summons 2-4 blue spiders.

Upon use increases damage by 2 for the current room and by a further +50% if the character also has the Blood of the Martyr.

Drops a large bomb.

Isaac farts, sending out rock waves.

Spawns a blue spider or fly. Turns pickups in the room into blue spiders or flies.

When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.

Upon activation, 1 coin will be consumed, and a random pickup may drop, similar to the slot machine.

Spawns a random charmed boss.

Triggers the effect of a random activated item from a list of possible options (not every activated item is included).

Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.

Shoots 10 tears in a circle around Isaac, which retain the damage, shot speed, and special effects (such as poison) of Isaac's tears.

Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal.

Removes one red heart container in exchange for gaining 3 Soul Hearts.

Upon use, Isaac farts, charming all nearby enemies.

Upon use, inflicts fear to all enemies in the room for 5 seconds.