Item: Celtic Cross

Grants a familiar that can block enemy shots.

Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins.

Increases speed by 0.3.

Isaac has a random chance to fire a Holy tear, which, when it hits an enemy, will spawn a Crack the Sky-style light beam on the same enemy, dealing damage.

Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.

-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.

Gives 5 bombs and grants all bombs poison effect.

Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.

Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.

Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.

Each time Isaac kills an enemy, Isaac's damage increases for the current room.

Adds 99 bombs.

Gives a random chance for projectiles to fire in all 4 cardinal directions.

+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.

A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.

Increases speed by 0.3.

An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.

Adds a chance to shoot poison tears, dealing damage over time when inflicted.

Increases Shot Speed, and drops a Tarot Card when picked up.

Allows Isaac to hold 1 additional trinket.