+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup.
Decreases damage and replaces right eye tears with a unlimited range, piercing laser which fires continuously.
Crown of Light
Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Lord of the Pit
Grants flight and increases speed.
Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.
Tears bounce off walls, enemies, and environmental objects.
-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.
When Isaac is hit, 1 point of an item's charge is filled.
A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies.
If the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room.
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
The Black Bean
When taking damage, Isaac farts, causing poison damage to all enemies in range.
Two items spawn in every Treasure Room. Only one can be taken; the other will disappear.
When hit, summons a white attack fly similar to Distant Admiration for the current room.
Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.