Spawns a pile of poop where the character is standing and knocks nearby monsters back. May yield pickups like regular poop.
Isaac releases bad gas, poisoning any enemy in close vicinity.
When used, places an explosive TNT barrel that can be pushed and used to destroy rocks or damage enemies. If used a second time in the same room while the previous TNT barrel is still intact, it will remotely explode the TNT.
Spawns a trapdoor that leads to the next floor upon activation. Unlocks The Forgotten when used on a mound of dirt that appears in The Dark Room.
Upon activation, Isaac gains a black heart.
Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
Upon use, for the next two seconds, any enemy shots that come near Isaac are held in place. After the charge is depleted, they are fired back as tears.
Passively grants flight and increased speed. Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies.
Deploys a decoy Isaac that eventually explodes with an increased blast radius.
Hurts Isaac without depleting health, activating any items that trigger upon taking damage.
Grants a random item effect for the current room.
Consumes Isaac's currently held trinket and applies its effect permanently.
Throws out a blue flame that can pass over gaps (but not through rocks). The flame damages anything in its path.
When used, converts two soul hearts into a heart container.
When used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).