Item: Dad's Key

When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.

Rerolls all of Isaac's items.

Every time Isaac kills an enemy, a fly will be added to the jar, up to a maximum of 20. Using the Jar of Flies will release all the flies that are currently in the jar as friendly blue flies that will damage enemies.

Spawns a blue spider or fly. Turns pickups in the room into blue spiders or flies.

Isaac holds the axe above his head for as long as the spacebar button is held (or until he leaves the room). While holding the axe, Isaac can break any rock he touches, but cannot attack or pick up other items.

Drops a large bomb.

Removes a heart container, increases damage and range, and grants a Cube of Meat.

Teleports you to a random room on the level.

Upon activation, enemies and their projectiles are slowed down for a short duration.

Upon use, spawns certain pickups or itemsdepending on the floor it is used on. Single-use.

Transforms Isaac into another random character.

Isaac farts, sending out rock waves.

Upon use, spawns a charmed Bony or an orbital bone for each enemy killed in the current room.

Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage.

While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.

Upon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the blood donation machine.

Duplicates all pickups and item pedestals in the room.

Deploys a decoy Isaac that eventually explodes with an increased blast radius.

Isaac farts and pushes back nearby enemies.

Upon use, makes a random item from a shop, devil deal, or black market free.