Definition of Category

Category
Item ID
Icon
Description

Best Friend

136
Best Friend
Deploys a decoy Isaac that eventually explodes with an increased blast radius.
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The D6

105
The D6
Allows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool.
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Brown Nugget

504
Brown Nugget
Spawns a stationary fly familiar that fires tears at nearby enemies.
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Caffeine Pill

340
Caffeine Pill
Increases speed and reduces character size. Also gives a random pill.
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Pointy Rib

544
Pointy Rib
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
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Friendly Ball

382
Friendly Ball
Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be charmed until it dies, persisting between floors.
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IV Bag

135
IV Bag
Upon activation, Isaac loses a half-heart (one whole heart in The Womb onwards) for a random amount of coins, similar to the blood donation machine.
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Number One

6
Number One
+1.5 tears, -15.77 range
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GB Bug

405
GB Bug
A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
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Converter

296
Converter
When used, converts two soul hearts into a heart container.
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Guppy's Tail

134
Guppy's Tail
Increases chance of finding gold chests and normal chests, but reduces chance of finding pickups.
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Breakfast

25
Breakfast
Grants Isaac one full red heart container.
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My Shadow

433
My Shadow
Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black Charger familiar that will attack enemies. The Charger will be killed if it is damaged too much.
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The Nail

83
The Nail
Adds one soul heart and allows the breaking of rocksand damaging enemies by simply walking over them. Increases damage and decreases speed. All effects except for the Soul Heart wear off upon leaving the room.
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Sticky Bombs

367
Sticky Bombs
+5 bombs. Bombs stick to enemies and spawn 2-4 blue spiders if they kill an enemy.
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Magic Mushroom

12
Magic Mushroom
Increases all stats and enlargens Isaac.
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Mom's Pearls

355
Mom's Pearls
+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
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Milk!

436
Milk!
A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.
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Breath of Life

326
Breath of Life
Grants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.
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Mr. ME!

527
Mr. ME!
Summons a controllable ghost that can perform various tasks depending on what it targets.
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