Definition of Use
Use
Item ID
Icon
Description
387
Censer
Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
118
Brimstone
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
18
A Dollar
Gives Isaac 99 coins. Can be found multiple times in a single playthrough.
421
Kidney Bean
Upon use, Isaac farts, charming all nearby enemies.
461
Parasitoid
Adds a chance to fire an egg sack which spawns slowing creep and spawns a blue fly or spider upon hitting an enemy.
159
Spirit of the Night
Grants spectral tears and flight.
21
The Compass
Reveals all special rooms (except secret rooms of any kind).
299
Taurus
Speed down; gains speed while in a room with enemies until gaining My Little Unicorn effect for a few seconds.
222
Anti-Gravity
-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.
437
D7
Restarts the current room and brings back all enemies, allowing more rewards to be acquired by completing the room.
439
Mom's Box
When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.
107
The Pinking Shears
Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage.
428
PJs
Grants four soul hearts and fully restores Isaac's red health.
58
Book of Shadows
Upon use, creates a protective shield nullifying all types of damage for 10 seconds.
212
Guppy's Collar
Grants Isaac a permanent 50% chance to respawn with 1/2 of a red heart after death.