+5 Bombs. Upon exploding, bombs shoot 8 tears off in every direction, similar to Tammy's Head. The tears are affected by any tear modifiers Isaac has on his own tears.
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
Spawns a familiar that flies the room while firing, dealing double Isaac's tear damage to enemies that come in contact and retrieving pickups.
Mom's Coin Purse
Spawns 4 random pills around Isaac.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).
Shows secret and super secret room locations on the map.
Upon taking damage, grants a body part as an orbital, which blocks enemy shots and deals 7 damage per tick to enemies it comes in contact with. The orbitals will be destroyed if they take enough damage from enemies or enemy shots.
Spawns a familiar that fires clusters of tears. Must be charged before shooting.
Isaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.
Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
Prevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear.
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Converts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup.
Spawns a familiar that follows Isaac around and fires tears with random effects.
Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.
Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.
-1 Tear Delay, adds knock-back shots and increases tear size.