Item: Friendly Ball
|Description||Throwing the ball at an enemy instantly kills it and captures it. The captured enemy can later be released and will be charmed until it dies, persisting between floors.|
|Quote||Gotta fetch 'em all!|
Reveals the map (except the Super Secret Room) and drops a random Tarot Card or soul heart.
Book of Revelations
Adds 1 soul heart, increases the chance for a Devilor Angel Room to appear, and increases the chance for the next boss to be a Horseman (except on XL floors and floors with fixed bosses such as Mom).
The Book of Sin
Spawns a random pickup, pill, card, or trinket.
Box of Friends
Upon use, duplicates all of Isaac's familiars for the current room.
Allows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool.
The Pinking Shears
Separates Isaac's head and body for the current room. Isaac's head, which now has flight, will be under the player's control, while his body will seek out enemies to attack by contact damage.
When used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
Damages all enemies in the room significantly.
Teleports you to a random room on the level.
Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
Isaac holds the axe above his head for as long as the spacebar button is held (or until he leaves the room). While holding the axe, Isaac can break any rock he touches, but cannot attack or pick up other items.
Spawns 2-4 blue flies to damage enemies.
Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades.
Mom's Bottle of Pills
Gives Isaac a random pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.
Deploys a decoy Isaac that eventually explodes with an increased blast radius.
Breath of Life
Grants a brief moment of invincibility when the charge bar hits zero. If spacebar is held for an additional second after hitting zero, Isaac will take damage.
Upon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.
Re-rolls all rocks in the current room into other random objects, such as bomb rocks, metal blocks, TNT, or poops.