Item: Ghost Baby
Increases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle.
Destroys rocks upon contact with Isaac. Adds one heart container and lowers Speed.
Taking damage releases a ring of 10 high damage tears.
Key Piece 2
Combined with Key Piece 1, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
A familiar that follows Isaac around shooting blood tears.
Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Eye of Belial
Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
Grants the combined effects of the Blue Map, Treasure Map, and The Compass, revealing the floor layout and all special rooms, including Secret Rooms and Super Secret Rooms.
Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, it stops moving.
Isaac leaves a trail of black powder on the floor. Walking in a circle will spawn a pentagram symbol on the floor, which deals 10 damage per tick to any enemies inside it.
Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs.
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds. Also converts "bad pills" into "good pills".
Ball of Tar
Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
Isaac can hold 2 cards at once and all pills are replaced by cards.
Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.
Transforms Isaac's tears into a wide arc shape which gives them a much larger hitbox. Gives Isaac spectral tears which allows them to travel through objects in the environment (i.e. rocks).