Item: Gnawed Leaf
Magic 8 Ball
Increases Shot Speed, and drops a Tarot Card when picked up.
An angel familiar which follows Isaac and fires homing tears which deal 10 damage at -25% shot speed and a reduced fire rate.
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
Increases damage as Isaac receives damage. Damage increase stays for the whole floor.
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Fliesdamaging enemies it passes through.
Isaac gains a shield that protects him from enemy shots.
Replaces tears with a piercing laser with unlimited range.
Each time Isaac takes damage, inflicts fear on all enemies in the room and spawns a black Charger familiar that will attack enemies. The Charger will be killed if it is damaged too much.
Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, it stops moving.
After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
Tears fired from left eye do increased damage.
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed.
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
Zodiac will give Isaac a random zodiac item effect that changes after every floor.
Greatly increases the chance to find sacks.