Item: Growth Hormones
A familiar that mirrors the player's movements and shoots in the opposite direction.
Gives "Turdy Touch" Effect. Enemies that touch Isaac are changed into poop.
Isaac's tears gain a random effect that changes every shot.
Reveals all special rooms (except secret rooms of any kind).
Spawns an egg familiar, which cracks and turns into a random charmed enemy when Isaac is hurt. The egg regenerates upon entering a different room.
Circle of Protection
Surrounds Isaac with a large white halo around him that pulsates. With each pulse, the halo deals contact damage to enemies equal to Isaac's damage. Each pulse also converts any enemy shots touching the ring into friendly purple homing tears.
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
Tears are replaced with piercing white blasts of light.
Grants an empty heart container. Increases damage, range and shot height while reducing speed.
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Whenever a Devil or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.
Allows Isaac to hold 1 additional trinket.
-2 Tear Delay. Tears float in position until firing ceases, after which they will fly off in the direction they were shot in.
Guppy's Hair Ball
Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle. Grows bigger by killing enemies.
Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.