Item: Guppy's Paw
Upon activation, 1 coin will be consumed, and a random pickup may drop, similar to the slot machine.
Has the same effect as the card or rune currently held by Isaac.
Reveals the map (except the Super Secret Room) and drops a random Tarot Card or soul heart.
Crack the Sky
Summons multiple beams of light in random locations around the room, dealing a large amount of damage to any enemy that touches them.
Rerolls the enemies in a room. Only rerolls enemies that are still alive (does not spawn new enemies).
When used, Mom's Box will drop a random trinket on the ground. While held, increases luck by 1 and doubles the effects of trinkets.
Forget Me Now
When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
Spawns 2-4 blue flies to damage enemies.
When at full health, up to 4 extra hearts can be stored in the jar.
When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head.
Isaac holds the axe above his head for as long as the spacebar button is held (or until he leaves the room). While holding the axe, Isaac can break any rock he touches, but cannot attack or pick up other items.
Upon use, spawns certain pickups or itemsdepending on the floor it is used on. Single-use.
Upon use, deals one heart of damage to Isaac and grants +1.2 damage for the current room.
If the box is empty, picks up all items and pickups in a room and stores them. If the box is not empty, places all stored items and pickups in the current room.
Upon use, inflicts fear to all enemies in the room for 5 seconds.
Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.