Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Chance to block projectiles coming from any direction.
Allows Isaac to carry two cards or pills (or a combination of both) at the same time.
Spider enemies no longer target or deal contact damage to Isaac.
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
Replaces tears with a piercing laser with unlimited range.
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
Increases damage by 0.5, tears by 0.7 and grants two soul hearts upon pickup.
Spirit of the Night
Grants spectral tears and flight.
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
Increases damage by 0.5, and multiplies it by 1.5x.
Replaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up.
Increases damage by 1, range by 5.25, and tear height by 0.5.
Isaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs.
Adds 3 Soul Hearts and increases the chance for The Bible to appear in any item pool.
Adds a chance to fire a gas cloud that damages nearby enemies.