Item: Hallowed Ground
Spawns allied blue spiders from killed enemies.
Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
1-3 Blue flies randomly spawn every time Isaac gets hit.
Isaac can hold 2 pills at once and all cards are replaced by pills.
Isaac's tears gain a random effect that changes every shot.
Cain's Other Eye
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeperand shoots normal tears in the same direction as Isaac.
Spawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy.
Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.
A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. If any enemies walk into its path, it will deal 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle.
Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears.
A bag that follows Isaac and drops a random rune every 3 rooms.
Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
Adds a chance to shoot fear tears and decreases tear delay by 1.