Item: Halo of Flies
Spawns a familiar that follows Isaac around and has a chance to drop a heart, coin, bomb, or keyafter clearing a room.
Grants an active item charge every 15 enemies killed.
A familiar that follows Isaac around shooting blood tears.
All sources of damage that would cause more than one half heart of damage are reduced to one half heart instead.
Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.
Spirit of the Night
Grants spectral tears and flight.
A Lump of Coal
The more distance tears travel, the more damage they will do.
A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.
A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.
Eye of Belial
Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
Isaac's tears split in two when they hit something.
Greatly increases the chance to find sacks.
Grants a chance to trigger the Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 10 seconds. Also converts "bad pills" into "good pills".
Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Grants one bone heart and spawns three red heart pickups.
Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
Increases speed by 0.3 and shot speed by 20%.