Item: Holy Grail
A white orbiting fly which deals 3 contact damage per tick to enemies. This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone.
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
Grants a familiar that transforms into another random familiar every 10 seconds.
Money = Power
Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins.
Spawns a familiar that fires clusters of tears. Must be charged before shooting.
Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.
An orbital angel which does 7 contact damage per tick and blocks enemy shots. Upon blocking 10 shots in a room it drops an eternal heart.
Shows secret and super secret room locations on the map.
Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.
Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies.
Ball of Tar
Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
Enemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.
Increases speed by +0.2 and grants piercing tears.
Grants Isaac one red heart container and fully restores Isaac's health.
Gives a random chance for projectiles to fire in all 4 cardinal directions.