Item: Holy Light
Spawns a familiar that follows Isaac around and collects red hearts. For every one-and-a-half red hearts collected, Dark Bum will generate one soul heart, one hostile Spider or one friendly blue spider.
Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.
Increases Damage by 1 and adds a chance to shoot fear tears.
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Follows Isaac around, shooting enemies with an eye laser similar to Technology.
Spawns a familiar that follows Isaac and makes other familiars follow it. While firing tears, it stops moving.
A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.
Gives 5 bombs and grants all bombs poison effect.
The Black Bean
When taking damage, Isaac farts, causing poison damage to all enemies in range.
Allows Isaac to carry two cards, pills, or any combination of both at the same time. Drops a random card or pill.
Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.
Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.
Increases Damage by 1.5, reduces Tears by 0.3 and increases tear size. Grants piercing tears. Tears are replaced by Death's scythes, which is a cosmetic effect only.
Sack of Pennies
Isaac is followed by a small bag that drops a coin every 2 rooms.
Adds a chance to reflect enemy shots. Grants one soul heart.
A portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickupafter collecting a coin. Does not spawn collectibles.
+1.7 tears, +0.3 speed, reduces damage.
A familiar that drops a Little Battery every 4 rooms. Has a small chance to freeze all enemies in the room when hit.
Maw of the Void
+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.