Enemies that touch you are stunned and turn gold. Any enemy killed while in this state will drop a coin.
Halo of Flies
Spawns two pretty fly familiars that block enemy shots and deal contact damage to enemies.
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
All types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage.
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
Increases damage by 0.5, and multiplies it by 1.5x.
Spawns a familiar that follows Isaac around and fires spectral tears.
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
Allows Isaac to carry two cards, pills, or any combination of both at the same time. Drops a random card or pill.
Shard of Glass
Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
Spawns a familiar that will follow Isaac's movements on a 2.5 second delay. Tears that pass through the baby will be doubled and increase in speed.
Follows Isaac and automatically fires at enemies in its reach.
While firing, Isaac gains a green aura that poisons nearby enemies.
Increases damage and increases the chance for a Devil or Angel Room to appear.
Circle of Protection
Surrounds Isaac with a large white halo around him that pulsates. With each pulse, the halo deals contact damage to enemies equal to Isaac's damage. Each pulse also converts any enemy shots touching the ring into friendly purple homing tears.
Increases Shot Speed and damage.
Activated Items can be "overcharged" to allow for an additional use.