Item: Isaac's Heart

Item

Description Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.
Quote Protect It
Item ID276
Icon Isaac's Heart
Category Possive Collectible
DLC Required None
Item ID
Icon
Description

9 Volt

116
9 Volt
Reduces the charge of any Activated Items by 1. Any 1 charge items instead have timed recharges.
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Shade

468
Shade
Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.
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There's Options

249
There's Options
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
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Multidimensional Baby

431
Multidimensional Baby
Spawns a familiar that will follow Isaac's movements on a 2.5 second delay. Tears that pass through the baby will be doubled and increase in speed.
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The Wiz

358
The Wiz
Tears simultaneously fire out of both eyes diagonally, similar to the effect of the R U A Wizard?pill. Isaac's tears also travel above all obstacles.
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The Ludovico Technique

329
The Ludovico Technique
Instead of firing tears, Isaac controls one floating tear that hover over obstacles. This tear deals constant damage when held in place over an enemy.
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Anemic

214
Anemic
+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room.
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Greed's Gullet

501
Greed's Gullet
Grants a heart container for every 25 coins Isaac has.
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Metal Plate

449
Metal Plate
Adds a chance to reflect enemy shots. Grants one soul heart.
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Leo

302
Leo
Allows you to crush rocks when you walk over them.
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Champion Belt

208
Champion Belt
Increases damage, but also increases the chance of champion enemies appearing.
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Crown of Light

415
Crown of Light
Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
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Jacob's Ladder

494
Jacob's Ladder
Tears fire sparks of electricity in random directions upon hitting an obstacle or enemy.
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The Mulligan

151
The Mulligan
Tears have a 1/6 chance of spawning allied blue flies when they hit an enemy.
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Samson's Chains

321
Samson's Chains
Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
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Tech.5

244
Tech.5
Grants a unlimited range piercing laser with random rate of fire that does not replace tears. The laser might occasionally fire with the effect of a random item or trinket, such as Hook Worm, Spoon Bender or Tiny Planet.
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Marbles

538
Marbles
Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
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Rune Bag

389
Rune Bag
A bag that follows Isaac and drops a random rune every 3 rooms.
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Ball of Bandages

207
Ball of Bandages
Orbiting familiar that deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Cube of Meat.
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Glaucoma

460
Glaucoma
Adds a chance to shoot concussive tears, causing enemies to walk around randomly.
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