Item: Jesus Juice
Blood of the Martyr
Increases Damage by 1, and turns Isaac's tears into blood tears.
Key Piece 1
Combined with Key Piece 2, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan.
Spawns 2 keys. Generates additional pickups from chests.
Increases range and shot speed, while adding 1 Black Heart.
A familiar that follows Isaac around shooting blood tears.
Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.
Grants a soul heart. Adds a chance to block enemy shots.
Grants charged tears that deal greater damage when fully charged.
1-3 Blue flies randomly spawn every time Isaac gets hit.
Isaac becomes camouflaged at the beginning of each room. Enemies will not attack Isaac until he starts firing tears.
Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Crown of Light
Gives Isaac a crown that glows blue when active, and turns gray when inactive. While Isaac has no empty red heart containers, Isaac's tears are replaced with blue diamond tears that deal double damage. Regardless of health, the crown will deactivate for the current room when Isaac takes damage.
Tears bounce off walls, enemies, and environmental objects.
If the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room.
Zodiac will give Isaac a random zodiac item effect that changes after every floor.
Sack of Pennies
Isaac is followed by a small bag that drops a coin every 2 rooms.
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.