Item: Key Bum
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.
Buddy in a Box
Grants a familiar with a random tear effect. The familiar is randomized at the start of each floor.
After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.
Activated Items can be "overcharged" to allow for an additional use.
Allows Isaac to carry two cards or pills (or a combination of both) at the same time.
Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving.
Adds a chance to fire a creep shot that deals double damage and leaves a trail of slowing white creep.
Spirit of the Night
Grants spectral tears and flight.
Grants one bone heart and spawns three red heart pickups.
Ball of Tar
Adds a chance to shoot slowing tears and the character leaves a trail of slowing creep behind as he moves, impeding enemies' speed.
Fires lasers at any enemy in its line of sight and moves based on the direction Isaac is firing tears.
Spawns a familiar that drops random pills every 2 rooms cleared. Upon using a pill, all enemies in the room are poisoned.
Grants quadruple shot but decreases tears.
Spawns an egg familiar, which cracks and turns into a random charmed enemy when Isaac is hurt. The egg regenerates upon entering a different room.
Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
Adds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
Tears leave a small, short lasting pool of creep on impact or when their range is depleted.
Converts all bad pills into good pills, spawns one pill pickup and restores health. Identifies all pills upon pickup.
All standard bomb pickups become 1+1 bomb pickups.