Item: Linger Bean
Increases tears by 0.4, and spawns 2 Soul Hearts pickups.
Grants one bone heart and spawns three red heart pickups.
???'s Only Friend
Summons a big attack fly that can be controlled with the shooting direction-keys.
Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.
Spawns an orbiting eye familiar that fires tears every 2 seconds.
Wanders about the room, occasionally spawning blue spiders.
Grants 5 bombs. Isaac's bombs leave behind fire that damages enemies upon contact.
When Isaac receives damage, the bottle breaks and a puddle of blue creep forms, which damages non-flying enemies, similar to Lemon Mishap. The bottle is reformed upon entering a different room.
Spawns a bone familiar that circles around Isaac and reflects enemy shots.
Curse of the Tower
Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
Grants a full heart container, and a chance to regenerate a half-heart of health every minute of gameplay.
Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
Grants one Heart Container and gives 2 Soul Hearts.
Increases the size of blue spiders and Blue Flies and doubles the amount of damage they deal.
Cube of Meat
Orbiting familiar that blocks enemy shots and deals damage to enemies. If collected while already having one, makes the familiar evolve. Only drops from Horsemen. Similar to Ball of Bandages.
Adds a chance to fire a booger which sticks to enemies and poisons them.
Spawns a familiar that fires clusters of tears. Must be charged before shooting.
Increases damage by 1 and range by 5 for tears fired from the left eye.