Item: Little C.H.A.D.
Increases Speed and Shot Height and decreases Isaac's size, but lowers Range.
After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.
Adds a chance to fire needles. If a needle kills an enemy, it bursts into more needles.
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
Grants 5 bombs. Isaac's bombs leave behind fire that damages enemies upon contact.
Adds 25 to Isaac's coin count, capping at 99.
Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
Increases damage and increases the chance for a Devil or Angel Room to appear.
Grants a familiar that transforms into another random familiar every 10 seconds.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
A familiar who will drop a half red heart every 2 rooms.
Spawns a familiar that fires clusters of tears. Must be charged before shooting.
Blood of the Martyr
Increases Damage by 1, and turns Isaac's tears into blood tears.
A bag that follows Isaac and drops a random rune every 3 rooms.
After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
Using an activated item while it's not charged will charge it and Sharp Plug does 2 full heart damage to Isaac.