Item: Little Chubby
Shows secret and super secret room locations on the map.
When hit, summons a white attack fly similar to Distant Admiration for the current room.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
Charm of the Vampire
Heals the character for half of a red heart for every 13 monsters killed.
+2.25 Range Up. +1.5 Tear Height. Isaac's tears travel through walls and appear out of the opposite wall. Isaac's tears also travel over rocks and objects.
Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
+0.7 tears up. Grants a random item at the start of the next run.
Increases damage based on how many empty heart containers Isaac has.
Grants one Heart Container, +0.3 Damage, +0.2 Tears, +0.25 Range, +0.3 Speed, and +0.5 Tear Height.
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to Boom Fliesdamaging enemies it passes through.
Eye of Greed
Adds a chance to fire tears that temporarily stun enemies and turn them into gold. Any enemy killed while in this state will drop coins.
Isaac's tears gain a random effect that changes every shot.
Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.
Sack of Sacks
Spawns a sack familiar that has a chance to drop a sack upon clearing a room.
+5 range. After Isaac is damaged, a trail of red creep will be left behind Isaac until he leaves the current room.
Increases tears. Adds a chance to fire a high-damage razor blade.
Increases damage by a flat 0.1 and grants a soul heart. Enemies can randomly become briefly charmed or feared. Taking damage has a chance to spawn a rainbow poop.
Grants a unlimited range piercing laser with random rate of fire that does not replace tears. The laser might occasionally fire with the effect of a random item or trinket, such as Hook Worm, Spoon Bender or Tiny Planet.