Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
Sets your key count to the maximum of 99.
Isaac is followed by a small blue cross that will drop a Soul Heart every 4 rooms.
Isaac's tears gain a random effect that changes every shot.
Adds a chance to spawn blue spiders when firing tears. Restores 1 red heart.
Isaac can hold 2 pills at once and all cards are replaced by pills.
Increases damage based on how many empty heart containers Isaac has.
Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.
Increases range. Tears turn into bones, which shatter into 1-3 bone shards upon hitting an enemy or obstacle.
+5 bombs. Bombs stick to enemies and spawn 2-4 blue spiders if they kill an enemy.
Grants quadruple shot but decreases tears.
Tears leave a small, short lasting pool of creep on impact or when their range is depleted.
Increases damage and range while reducing shot speed and grants homing tears. Grants a Heart Container and replenishes all Red Hearts.
Spawns a familiar that will follow Isaac's movements on a 2.5 second delay. Tears that pass through the baby will be doubled and increase in speed.
Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
Grants 7 bombs and allows bombs to be placed rapidly.
Connects Isaac's tears with electricity that can damage enemies.
Spawns an egg familiar, which cracks and turns into a random charmed enemy when Isaac is hurt. The egg regenerates upon entering a different room.