Item: Marked

Grants Isaac one red heart container and fully restores Isaac's health.

A trail of blue creep is left behind Isaac, which damages enemies.

Combined with Key Piece 2, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan.

Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering The Necronomicon effect.

Follows Isaac around shooting normal tears.

Grants one red heart container, restores 5 red hearts, and increases speed by 0.3.

Adds a chance to shoot fear tears and decreases tear delay by 1.

+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.

Grants one full red heart container.

Grants the player one red heart container, one soul heart, and one black heart.

Grants an active item charge every 15 enemies killed.

Increases tears. Adds a chance to fire a high-damage razor blade.

Increases Tears by 0.7.

Increases the size and damage of familiars.

Spawns a familiar that flies the room while firing, dealing double Isaac's tear damage to enemies that come in contact and retrieving pickups.

Grants one bone heart and spawns three red heart pickups.

Tears up, adds 1 soul heart, and decreases Isaac's size.

Adds a chance to fire tears that temporarily stun enemies and turn them into gold. Any enemy killed while in this state will drop coins.

Reveals and opens all Secret Room and Super Secret Room entrances.

Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeperand shoots normal tears in the same direction as Isaac.