Item: Missing No.
Blood of the Martyr
Increases Damage by 1, and turns Isaac's tears into blood tears.
Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed.
Grants an active item charge every 15 enemies killed.
Shooting in one direction increases Isaac's rate of fire until the cap is reached. As soon as Isaac changes direction or stops shooting, rate of fire is reset to its normal amount.
Isaac's tears gain a random effect that changes every shot.
Increases Speed and Shot Height and decreases Isaac's size, but lowers Range.
Curse of the Tower
Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
Grants Isaac piercing tears that travel through enemies (but not obstacles) instead of breaking on impact with them.
Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. Shrunk enemies can be crushed and killed by walking over them.
Increases damage and grants a charged shot that fires multiple tears in the same fashion as Monstro.
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
Spawns a blue attack fly that orbits a long distance from Isaac.
After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
+5 bombs. Bombs stick to enemies and spawn 2-4 blue spiders if they kill an enemy.
When hit, spawns up to 2 blue spiders.