Item: Mom's Underwear
Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkable sections.
Upon dying, resurrect as Revived Lazarus with one heart container and Anemic item.
Increases speed by +0.2 and grants piercing tears.
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
Adds one filled heart container and increases Shot Speed.
Grants Isaac one full red heart container.
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
When hit, summons a white attack fly similar to Distant Admiration for the current room.
Isaac himself is now immune to all damage, and a heart familiar appears and follows Isaac. If the heart is hurt, Isaac is hurt.
Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range.
Spawns allied blue spiders from killed enemies.
Dad's Lost Coin
Increases range by 1.5. Drops a lucky penny.
Curse of the Tower
Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic.
Increases range and shot height.
Spawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.
Replaces all red hearts with 6 empty bone hearts. Upon losing a bone heart, Isaac fires bones in 8 directions and permanently gains a tears up.
Tears fired from left eye do increased damage.
Grants 2 Heart Containers and completely restores health.