Item: Monstro's Tooth
Freezes all enemies until a fire button is pressed.
Forget Me Now
When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
Dead Sea Scrolls
Triggers the effect of a random activated item from a list of possible options (not every activated item is included).
Throws a persistent flame that deals high damage and diminishes as it damages enemies or blocks shots.
Upon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.
Damages all enemies in the room significantly.
Isaac farts and pushes back nearby enemies.
Damages all enemies in the room, but deals a heart of damage to Isaac with each use.
Isaac releases bad gas, poisoning any enemy in close vicinity.
Rerolls the enemies in a room. Only rerolls enemies that are still alive (does not spawn new enemies).
Upon activation, Isaac gains flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart, and It Lives when activated, but will kill Isaac when activated while fighting Satan.
While held, causes multiple Mom's Foots to come down and stomp on Isaac. One of two parts necessary to create Mom's Shovel.
Damages all enemies in the room and slows them and their projectiles down.
Teleports you to a random room on the level.
Creates an explosion in the same area as Isaac, dealing half a heart of damage to him and also damaging all enemies caught in the blast radius.
Box of Friends
Upon use, duplicates all of Isaac's familiars for the current room.
For 1 coin, damages all enemies in the room.