Item: Mutant Spider
Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
Increases damage by 1 and range by 5 for tears fired from the left eye.
Grants a heart container for every 25 coins Isaac has.
Has a chance to fire tears that inflict bleeding on enemies, causing them to slowly take damage over time.
After Isaac takes damage, this fly will deal continuous touch damage to whatever enemy caused the damage until it is dead. The fly will then systematically attack 1 enemy at a time until the room is cleared.
Has a chance to drop a random pickup when Isaac takes damage.
Displays Isaac's tear damage and enemy health bars. Spawns a gray spider familiar that wanders around and inflicts a random status effect on any enemies it comes into contact with. Occasionally spawns a blue spider upon clearing a room.
Eye of Belial
Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.
Spawns a familiar that drops random pills every 2 rooms cleared. Upon using a pill, all enemies in the room are poisoned.
Increases damage, and adds 1 heart container.
Isaac becomes camouflaged at the beginning of each room. Enemies will not attack Isaac until he starts firing tears.