Item: Number One
1-3 Blue flies randomly spawn every time Isaac gets hit.
Grants piercing and spectral tears. Increases tear size (without increasing damage) while greatly reducing range and shot speed.
A familiar that drops a Little Battery every 4 rooms. Has a small chance to freeze all enemies in the room when hit.
Isaac heals 1 heart instead of taking damage from an explosive source. Adds 5 bombs.
Tears fired from left eye do increased damage.
Adds a chance to shoot fear tears and decreases tear delay by 1.
Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Spawns a cloud familiar that leaves a trail of tears that damages enemies. Has a chance to spawn damaging beams of light onto enemies that touch the cloud.
Spawns a familiar that follows Isaac around and fires tears with random effects.
Inflicts poison to enemies who make contact with Isaac. Speed down.
Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any red hearts, these benefits will disappear.
Tears shrink and do much less damage, but fire in very rapid succession.
Spawns a familiar that follows Isaac around and blocks enemy projectiles. Upon blocking a shot, it has a chance of triggering The Necronomicon effect.
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Spawns a chest familiar that follows Isaac and drops a random pickup every few rooms.
Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving.
A host familiar that sits on Isaac's head and has a random chance to block enemy shots and retaliate with 3 tears. Grants immunity to explosions.