One time use Items


Welcome to The Binding of Isaac item guide. Click on an item to learn more.

Item ID
Icon
Description

Pandora's Box

297
Pandora's Box
Upon use, spawns certain pickups or itemsdepending on the floor it is used on. Single-use.
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Forget Me Now

127
Forget Me Now
When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.
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Sacrificial Altar

536
Sacrificial Altar
Upon use, sacrifices up to 2 familiars and spawns an item from the Devil Room Pool for each familiar sacrificed.
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Plan C

475
Plan C
Kills all enemies in the room, then kills Isaac three seconds later.
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Mystery Gift

515
Mystery Gift
Upon use, spawns a random item from the current room's item pool, with a chance to spawn A Lump of Coal or The Poop instead.
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Mama Mega!

483
Mama Mega!
Damages all enemies and destroys all obstacles. The effect occurs every time a new room is entered for the rest of the floor. Opens doors to the floor's secret and super secret rooms.
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Eden's Soul

490
Eden's Soul
Spawns two item pedestals.
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Diplopia

347
Diplopia
Duplicates all pickups and item pedestals in the room.
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