Item: Pointy Rib
Grants an active item charge every 15 enemies killed.
Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Sack of Pennies
Isaac is followed by a small bag that drops a coin every 2 rooms.
Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.
Tears and Range up. Spawns 3 random types of hearts on the floor when picked up.
Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. In the burst of tears is a kidney stone which deals a lot of damage.
Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.
There will be 2 items available to choose from after defeating a boss. Choosing 1 item causes the other to disappear.
Allows Isaac to hold 1 additional trinket.
Follows Isaac around, shooting enemies with an eye laser similar to Technology.
A familiar who will drop a half red heart every 2 rooms.
+0.7 tears up. Grants a random item at the start of the next run.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
If the character has half a red heart or no red hearts after taking damage, it triggers The Necronomicon effect, damaging all enemies in the room. Also allows entrance into the Dark Room.
Adds a chance to shoot a tooth instead of a tear, which deals greater damage than regular tears.
Reveals and opens all Secret Room and Super Secret Room entrances.