Item: Poke Go

Gives a random chance for projectiles to fire in all 4 cardinal directions.

Grants a familiar that can block enemy shots.

A familiar fly that moves in a straight line and attaches itself to the first obstacle or wall it comes into contact with in each room. If any enemies walk into its path, it will deal 7 contact damage per tick. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle.

Adds a chance to reflect enemy shots. Grants one soul heart.

Spawns a familiar that follows Isaac around and fires tears with random effects.

Tears now have a random chance to apply a poison effect, causing 4 or 6 damage per tick to enemies (Similar to The Common Cold item). Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick). Enemies that were poisoned have a chance to drop a black heart when killed.

A portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickupafter collecting a coin. Does not spawn collectibles.

Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.

Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.

Summons a familiar that copies the tears of Isaac's other familiars.

A blue head familiar that will follow Isaac and fire tears copying his tear effects and damage.

Grants spectral tears and flight.

Doubles damage, halves tears stat, and greatly reduces shot speed.

Grants 2 Heart Containers and completely restores health.

Spawns a Mulligan Familiar that will wander the room randomly. Enemies will attack the Mulligan if it's closer.

Isaac's damage increases each time an enemy is hit. Damage is reset upon missing a shot.

Randomizes all passive items upon pickup and at the start of each succeeding floor.

Surrounds Isaac with a large white halo around him that pulsates. With each pulse, the halo deals contact damage to enemies equal to Isaac's damage. Each pulse also converts any enemy shots touching the ring into friendly purple homing tears.

Increases speed by 0.3 and shot speed by 20%.

Isaac can hold 2 pills at once and all cards are replaced by pills.