Increases damage by 0.3 and adds a chance to shoot concussive tears, causing enemies to walk around randomly.
Spawns a familiar that follows Isaac around and fires homing tears.
Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player. This allows for a full 360 degree tear firing radius. Can be overridden by other tear modifiers such as Mom's Knife or Brimstone.
A Familiar that shoots a thin Brimstone beam. Must charge like Brimstone before shooting.
A glitch familiar that bounces around the room and applies a random status effect to any enemies it comes into contact with and has a chance to re-roll pickups that it passes over.
Gives Isaac a golden censer familiar which creates a huge aura of light that slows down any enemies and enemy shots inside it.
Increases speed by 0.3 and shot speed by 20%.
Lord of the Pit
Grants flight and increases speed.
Grants the player one red heart container, one soul heart, and one black heart.
While Isaac has no red hearts, this item grants flight and a random chance to activate an invincibility shield for a few seconds. If Isaac gains any red hearts, these benefits will disappear.
Adds a chance to shoot slowing tears, reducing speed of enemy movement and any projectile fired by them.
Replaces tears with a piercing laser with unlimited range.
Increases damage by 1 and range by 5 for tears fired from the left eye.
A familiar that follows Isaac and blocks tears. If a tear hits Farting Baby, there is a high chance for it to fart, which will either knock back, poison, or charm all nearby enemies.
An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Increases Luck by 1, grants 1 Soul Heart and spawns 2 Keys.
Spawns an orbiting eye familiar that fires tears every 2 seconds.
Gives Isaac a Gurdy familiar that will charge around the room dealing contact damage to enemies. Lil Gurdy is charged by holding down a fire button and letting go. The longer the button is held, the faster Lil Gurdy will fling itself across the screen. Lil Gurdy can pass over objects and obstacles in the room.