Item: Sad Bombs
Increases Damage by 1 and adds a chance to shoot fear tears.
Pull a chain and ball behind you that will damage enemies on contact and is able to break stones.
Spawns a beggar familiar which floats around the room and picks up any nearby coins, leveling up after collecting several coins. At level 2, Bumbo gains a body. At level 3, it begins to fire tears. At level 4, Bumbo chases enemies slowly, dealing contact damage.
This item will boost one of Isaac's stats depending on the color of the aura around him. The aura will disappear upon taking damage and will reappear with a random color upon entering a new room. A red aura boosts damage, a blue aura boosts rate of fire, a yellow aura boosts speed, and an orange aura boosts range.
Tears are replaced by a laser beam that pierces through all enemies and obstacles in its path and deals high damage. Can only be fired after a short charge-up period.
Buddy in a Box
Grants a familiar with a random tear effect. The familiar is randomized at the start of each floor.
Drops a random trinket. Grants a second trinket slot.
Tears bounce off the floor. Tears that hit an enemy after bouncing deal splash damage to all nearby enemies for 25% of Isaac's tear damage.
Allows Isaac to carry two cards or pills (or a combination of both) at the same time.
Adds a chance to fire a piercing tear that instantly kills any enemy that it touches.
+1.25 Range Up. +0.5 Tear Height. +1 Luck Up.
An orbital angel which does 7 contact damage per tick and blocks enemy shots. Upon blocking 10 shots in a room it drops an eternal heart.
Increases speed and reduces character size. Also gives a random pill.
Spawns 3 random trinkets. Taking damage has a small chance to swallow Isaac's currently held trinket, gaining its effect permanently.
Pay to Play
This item turns all doors that require a key into doors which need a coin to enter instead. This affects shops, item rooms, libraries and other key doors.
Spawns a random pill, and grants a small Spewer familiar that charges up and fires different types of creep.
Replaces tears with explosive and poisoning projectiles fired in an arc from the mouth.
Grants charged tears that deal greater damage when fully charged.
Charm of the Vampire
Heals the character for half of a red heart for every 13 monsters killed.