A familiar that mirrors the player's movements and shoots in the opposite direction.
Spawns an orbiting razor that damages enemies it touches and inflicts bleeding on enemies, causing them to slowly take damage over time.
Sets your key count to the maximum of 99.
Suture becomes attached to Isaac, and does touch damage to enemies within its attacking range.
Spawns a blue attack fly that orbits a long distance from Isaac.
Increases the size of blue spiders and Blue Flies and doubles the amount of damage they deal.
A purple fly familiar that follows Isaac's movements on a 3 second delay and deals contact damage to enemies.
Isaac's tears have a chance to stick to enemies and explode.
Isaac can hold 2 cards at once and all pills are replaced by cards.
A bag that follows Isaac and drops a random rune every 3 rooms.
A cone of light shines in the direction Isaac is moving that slows enemies and enemy shots.
+0.25 Speed. Running into enemies while at a high speed will deal 18 points of damage. Does not prevent contact damage.
An Angel Room door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
A trail of blue creep is left behind Isaac, which damages enemies.
All types of fly except Boom Fly and Red Boom Fly become passive and slowly move towards Isaac. Does not prevent contact damage.
Upon death, the player will respawn as ??? with 3 soul hearts.
Tears fired from left eye do increased damage.