Increases damage as Isaac receives damage. Damage increase stays for the whole floor.
Adds one empty heart container. Whenever Isaac takes damage there's a chance that a Red Heart may drop.
Grants 2 Heart Containers and completely restores health.
Tears are replaced by bombs that benefit from bomb-enhancing effects and slide a fixed range after being fired.
Every tear has a small shield which will allow it to block one enemy projectile.
Causes shops to instantly restock their items when they are bought. Granted by default for every character in Greed Mode.
Increases damage, and adds 1 heart container.
Increases range and shot height.
Range up and makes shot tears revolve around Isaac until they drop.
Upon entering a room, poisons all enemies, dealing double Isaac's tear damage. Killing enemies leaves a small, short lasting pool of green creep on the ground.
Adds a chance to shoot petrifying tears, which stop enemies in place and prevent them from moving or attacking. Range up.
Pay to Play
This item turns all doors that require a key into doors which need a coin to enter instead. This affects shops, item rooms, libraries and other key doors.
Grants a random Harbinger familiar that changes every 10 seconds.
Lord of the Pit
Grants flight and increases speed.
Grants a prism orbital with a large orbital radius. Tears that pass through the prism split into four multi-colored tears.
Continuously firing tears for several seconds causes Isaac to drop a Butt Bomb. Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time.
Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving.
Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.