Item: Shard of Glass

Increases Damage by 1.

Grants 1 heart container and increases tears, but decreases shot speed.

Spawns a flying familiar for the current room that chases enemies whenever Isaac takes damage.

Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.

Upon entering a room with enemies in it, has a chance to spawn a random charmed enemy that persists across rooms.

Grants flight.

Grants flaming tears that deal burning damage over time. Tears have a chance to explode on impact with an enemy, which creates a fire at the location of the explosion.

Combined with Key Piece 2, unlocks the golden gate in the starting room of The Chest and Dark Room to fight Mega Satan.

A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.

After standing still and not shooting for a short time, Isaac turns invincible until he moves or shoots.

Spawns a shadow familiar that follows Isaac's movements on a 1 second delay and deals contact damage to enemies.

Isaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.

Adds 3 black hearts and increases Damage by 1.

A blue fly familiar follows Isaac's movements on a 3 second delay. Papa Fly will fire tears at nearby enemies.

If the character has half a red heart or no red hearts after taking damage, it triggers the Book Of Shadows effect, creating a shield that nullifies all types of damage for 5 seconds. Also allows entrance into The Chest.

Adds 5 bombs. Isaac's bombs explode into 2-4 tiny bombs.

All sources of damage that would cause more than one half heart of damage are reduced to one half heart instead.

A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.

Increases damage by 0.04 for every coin Isaac has, up to +3.96 damage at 99 coins.

Prevents curses. Grants one black heart. Increases the chance for a Devil or angel room to appear.