Item: Sharp Straw
Duplicates all pickups and item pedestals in the room.
How to Jump
Gives Isaac the ability to jump (over gaps, spikes, etc.).
When used, has a 50% chance to drop one random type of coin (penny, nickel, or dime).
Upon use, Isaac farts, charming all nearby enemies.
Grants a random item effect for the current room.
When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.
Upon use, grants invulnerability and increased speed for five seconds, but removes the ability to shoot tears.
Shoots 8 tears around Isaac, which retain the damage, shot speed, and special effects of his tears. Each tear shot by Isaac increases item charge by one.
When used, places an explosive TNT barrel that can be pushed and used to destroy rocks or damage enemies. If used a second time in the same room while the previous TNT barrel is still intact, it will remotely explode the TNT.
Summons a random familiar for the current room. Can summon familiars not yet unlocked.
Can be used to place an orange portal and a blue portal. Upon entering a portal, Isaac is teleported to the other portal.
Reveals the map (except the Super Secret Room) and drops a random Tarot Card or soul heart.
Damages all enemies in the room significantly.
When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head.
When used, reduces Isaac's health to half a heart (including soul and black hearts) and fires one large piercing spectral tear that does a lot of damage. The damage done by Glass Cannon scales with Isaac's damage (at base damage it does 45 damage).
Upon use, Isaac fires a laser similar to the one used by Mega Satan. This laser deals massive damage, lasts for approximately 15 seconds, and persists between rooms. Isaac is pushed backwards by the force of the laser while it is active.
Spawns a penny and has a 50% chance to double all items and pickups in the room. If the effect fails, the items and pickups disappear.
Consumes all pedestal items in the room. Active items will have their effects added to Void, and passive items will grant stat upgrades.
Book of Shadows
Upon use, creates a protective shield nullifying all types of damage for 10 seconds.