Item: Speed Ball
Cain's Other Eye
Spawns a familiar that floats slowly around the room on a zig-zag pattern similar to The Peeperand shoots normal tears in the same direction as Isaac.
Magic 8 Ball
Increases Shot Speed, and drops a Tarot Card when picked up.
Increases speed by 0.3 and shot speed by 20%.
Spawns a bone familiar that circles around Isaac and reflects enemy shots.
+5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects troll bombs.
Gives 3 pennies on pick-up. Every time Isaac is damaged, he will drop one additional penny.
Spawns a Hush familiar that bounces around the room and deals contact damage. While firing tears, it stops moving.
Shard of Glass
Upon taking damage, Isaac has a chance to drop a full red heart, gain 5 range, and leave a trail of damaging red creep for the current room.
Spawns a bone familiar that can be aimed with the fire buttons and does contact damage.
Increases damage and range while reducing tears and shot speed. Grants homing tears and tears gain a damaging halo.
Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player. This allows for a full 360 degree tear firing radius. Can be overridden by other tear modifiers such as Mom's Knife or Brimstone.
Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.
The Common Cold
Adds a chance to shoot poison tears, dealing damage over time when inflicted.
Grants a reward if all enemies in a room are killed in the order they are marked.
Reduces all Shop prices by 50%, rounded down to 7 coins for an item, rounded up to 2-3 coins for a pickup.
A Devil Room / Angel Room Door will always spawn after every boss fight, excluding the first floor and floors after Utero II/Womb II.
Spawns 1 of each (non-collectible) item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.