Item: Spirit of the Night
Grants four soul hearts and fully restores Isaac's red health.
Gives +5 bombs and makes all bombs Butt Bombs that fill the room with gas, damaging and confusing all enemies.
Sets the amount of red heart containers to 1, but gives Isaac 9 extra lives. After dying, Isaac is teleported to the last safe room. New heart containers can be obtained after picking up this item, but after each death, the number of heart containers is set to 1 again.
Isaac becomes camouflaged at the beginning of each room. Enemies will not attack Isaac until he starts firing tears.
Grants spectral tears that travel through obstacles (but not enemies) instead of breaking on impact with them.
A portable beggar who follows Isaac, picks up coins for himself, and occasionally drops a pickupafter collecting a coin. Does not spawn collectibles.
Increases damage as Isaac receives damage. Damage increase stays for the whole floor.
Using an activated item while it's not charged will charge it and Sharp Plug does 2 full heart damage to Isaac.
Chance upon entering a room to slow down or speed up every enemy and their attacks. The chance to slow enemies is quite higher than the chance to speed them up.
Grants two soul hearts. Isaac now repels enemy projectiles.
Whenever Isaac takes damage, a black ring briefly appears around Isaac, dealing damage to all nearby enemies.
Maw of the Void
+1.0 Damage Up. After continuously firing tears for 2.5 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring that rapidly deals damage equal to Isaac's tear damage to any enemies in contact with it.
Spawns a white poop familiar, which turns into a white poop when Isaac is hurt.
Isaac's tears decelerate as they travel. Upon stopping or hitting an obstacle, they burst into 8 tears in all directions. Tears can be fired into other tears to feed them, increasing their damage.
+5 bombs. Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide). This also affects troll bombs.