Item: Squeezy

Grants piercing tears. After piercing one enemy, tears start homing and deal double damage.

Upon entering a room with enemies in it, has a chance to spawn a random charmed enemy that persists across rooms.

Whenever a Devil or Angel Room would spawn after defeating a boss, both rooms spawn. Only one can be entered.

Grants one red heart container, restores 5 red hearts, and increases speed by 0.3.

A glass of milk follows Isaac and spills on the floor upon taking damage. After the milk spills, Isaac's tear delay is decreased by 2 for the rest of the room.

Increases range and shot speed, while adding 1 Black Heart.

Gives Isaac's tears a boomerang effect, and increases range and shot speed.

Every time Isaac takes damage, a charm effect is applied to every enemy in the room, causing them to attack each other rather than Isaac.

Adds a chance to fire needles. If a needle kills an enemy, it bursts into more needles.

A red attack fly circles further out than the Halo of Flies / Pretty Flies, but closer than Forever Alone. Deals more damage than Forever Alone.

Causes Isaac's activated item to activate twice on each use.

Spawns a familiar that fires clusters of tears. Must be charged before shooting.

Tears up, adds 1 soul heart, and decreases Isaac's size.

Activated Items can be "overcharged" to allow for an additional use.

A Loki familiar that follows Isaac and shoots 4 tears in a cross pattern.

Summons a big attack fly that can be controlled with the shooting direction-keys.

Spawns 2 keys. Generates additional pickups from chests.

Spawns a familiar that follows Isaac around and fires two tears at once in a V-pattern.

Enemies, enemy shots, tears, and pickups will briefly freeze in place at random intervals.

Tears are now fired in an arc. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Increases tear delay.